Virtual reality AIRWAYS

As microbiologists, we are privileged to be able to envisage the microscopic world of bacteria and viruses that are seemingly invisible. We wanted to find a way to show non-specialists how phages can influence bacterial communities differently in the body. Together with immersive art practitioners, we co-created an immersive journey through the lungs of someone with cystic fibrosis.

You enter through the bronchus and then choose paths through the bronchioles where you can find multiple different bacteria that inhabit these airways. By increasing the magnification you join the microbial communities and watch how phages infect their target bacteria in one of with three very different alternative outcomes.

Inside the Lung: The user chooses a path to take… where they zoom in to meet key microbial players

The Cystic Fibrosis lungs are colonised by polymicrobial communities

THE PROTAGONISTS

Pseudomonas aeruginosa is the most common bacteria found in the lungs of people with cystic fibrosis. It is an opportunistic pathogen, that usually lives in soil or water, but can cause chronic infections that are very difficult to treat.

Some bacteriophages have been used to kill Pseudomonas aeruginosa bacteria in cystic fibrosis lung infections. but Others bacteriophages have formed partnerships with these bacteria, helping them to survive better in the lungs.

THE CREATIVE TEAM

 

VR-Airways was created in Unreal by Artist Paul Miller with technical input from Richard England of Reflex Arc. And scientific input from Chloe James (University of Salford),